Endocrine Abstracts

Aims: To evaluate the effect of Liraglutide on clinical parameters in obese Type 2 diabetic patients with inadequate glycemic control despite treatment with oral hypoglycaemic agents (OHAs) and insulin.Methods: Three hundred and fifty three (M:232, F:121) obese (according to Asian-Indian criteria) type 2 diabetic patients with inadequate glycemic control (HbA1c>7% & <10%) attending outpatients clinic on insulin and OHAs were initiated on lira...

Studies show conflicting results regarding possible excess risk of atypical fractures associated with bisphosphonate (BSP) use. Since BSP reduces bone remodeling, they freeze the skeleton allowing accumulation of microcracks over time leading to atypical fractures. We present two cases of atypical fracture and discuss on monitoring therapy and drug holiday in chronic BSP users.Methods: Over the period of last 8 months we diagnosed two cases of alendronat...

Introduction: 5 alpha-steroid reductase deficiency (5α SRD) is a rare autosomal recessive disorder. Presented here is the clinical profile and long term outcomes of subjects with 5α SRD examined in our hospital during the last 30 yrs.Methods: Records of patients registered in the endocrine clinic of our hospital and new patients with diagnosis of 5α SRD were compiled. Details of history,physical examination,chromosomal analysis, hormonal s...

Introduction: Primary Hypoparathyroidism presents most commonly in childhood to early adolescence. Disease may be familial or sporadic.Most commonly hypoparathyroidism is secondary to neck operations especially Thyroid surgeries. Primary can be congenital eg- Digeorge syndrome or inherited by AD, AR or X linked mediated.We report 2 cases of late onset seizure due to Digeorge syndrome and Autosomal Dominant Hypoparathyroidism in a elderly lady.Case Report...